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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Magnet-assisted transfection ： ウィキペディア英語版 Magnet-assisted transfection Magnet Assisted Transfection is a transfection method, which uses magnetic force to deliver DNA into target cells. Therefore, nucleic acids are first associated with magnetic nanoparticles. Then, application of magnetic force drives the nucleic acid-parcticle complexes towards and into the target cells, where the cargo is released.〔Plank et al. Magnetically enhanced nucleic acid delivery. Ten years of magnetofection-progress and prospects Adv Drug Deliv Rev. 2011 Nov;63(14-15):1300-31〕〔http://www.ozbiosciences.com/magnetofection.html〕 == The magnetic nanoparticles == Nanoparticles used as carriers for nucleic acids are mostly iron oxides.〔Plank, C., Schillinger, U., Scherer, F., Bergemann, C., Remy, J. S., Krötz, F., Anton, M., Lausier, J. and Rosenecker, J. (2003) Biol. Chem., 384, 737-747.〕 These iron oxides can be generated by precipitation from acidic iron-salt solutions upon addition of appropriate bases. The magnetic nanoparticles have an approximate size of 100 nm and are additionally coated with biological polymers to allow loading of nucleic acids. Particles and nucleic acids form complexes by ionic interaction of the negatively charged nucleic acid and the positively charged surface of the magnetic nanoparticle. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Magnet-assisted transfection」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.